By Neha MathurJan 17 2023Reviewed by Aimee Molineux In a recent article published in iScience, researchers demonstrated that individuals recovering from mpox virus infection have neutralizing antibodies that target MPXV antigens A35R and H3L.
These tests could be advantages, for they would require a non-biosafety level 3 point of care site only. Additionally, serological assays could help identify T cells, but more importantly, B cell markers, leading to the extraction of neutralizing antibodies that could later serve as therapeutics.About the study In the present study, researchers first expressed two MPXV antigens from the MV form and one from the EV form.
Drug Discovery eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy Finally, the team mapped three MPXV antigens elicited against either MPXV or VACV infection. These were A35R from the EV form, M1R, and H3L from the MV form.
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