Using the power of light to transform analytical workflows in the life sciences

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Using the power of light to transform analytical workflows in the life sciences refeynit interview LifeSciences technology Automation

Sponsored Content by RefeynJan 17 2023 insights from industrySvea CheesemanDirector of Product Management for Cell and Gene TherapyRefeyn In this interview, we speak to Svea Cheeseman at Refeyn about their SamuxMP products used for the analysis of adeno-associated viruses capsids as well as the role automation will play in accelerating new research.

Towards the end of 2023, we intend to bring a novel mass photometer to the market that measures larger viruses and lipid nanoparticles . How does Mass Photometry work? [with subtitles]Play Refeyn is focused on mass photometry, a new revolutionary method that analyzes molecules. Can you tell us more about how mass photometry works and its potential in bioanalytics? Mass photometry builds on the principles of two optical techniques: interference reflection microscopy and interferometric scattering microscopy.

But probably the most significant benefit of mass photometry is that it analyses samples molecule by molecule, giving unique information that is only accessible on the single-molecule level. Let's take protein-protein interactions as an example – suppose you want to analyze the binding of protein A to protein B. But if protein A exists in an equilibrium of monomers and dimers, mass photometry can distinguish if the monomer of A binds to protein B, the dimer binds, or both.

I will also give an overview of new products in the SamuxMP product line that will be available this year: The SamuxMP Auto, which is an automated mass photometer, as well as GMP-compliant software for using the SamuxMP and SamuxMP Auto in production and QC environments. Because the design is modular, existing customers of the SamuxMP can retrofit their system for automation. Also, the GMP-compliant software available in H2/2023 will be retrofittable for all SamuxMP and SamuxMP Auto customers.With new exciting technologies such as mass photometry allowing scientists to answer their research questions quickly, scientists can focus more on innovation.

As well as continuing to push the boundaries of single-particle analysis, you always aim to meet the needs of scientists and inspire new ideas. How do you do this, and why is it important for technology to evolve as science does? Scientific progress has always been a synergy between scientific discovery posing new questions and new technologies providing new answers.

 

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