, steady levels of estrogen can help ease both regular headaches and migraine attacks. However, when estrogen levels oscillate, which happens throughout a person’s life, migraine can get worse.During your menstrual cycle, estrogen naturally drops right after ovulation, then again just before your period starts, says Dr. Krel. “It is during these moments, when estrogen is lowest, that some women tend to experience more frequent migraine attacks,” she says.
, estrogen also has a protective effect against migraine—but when it fluctuates, so does serotonin, which could potentially trigger a migraine attack. Similarly, estrogen increases the release of gamma-aminobutyric acid , a neurotransmitter that reduces pain. But again, when estrogen fluctuates, so does GABA, which may also result in migraine attacks.Estrogen may also help protect against inflammation in the brain.
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