Eli Lilly said its highly popular weight loss drug Zepbound showed the potential to treat patients with the most common sleep-related breathing disorder in two late-stage clinical trials.
The results are an early sign of hope for the estimated 80 million patients in the U.S. suffering from OSA, which refers to interrupted breathing during sleep due to narrowed or blocked airways. Around 20 million of those people have moderate-to-severe forms of the disease, but 85% of OSA cases go undiagnosed, according to Eli Lilly., loud snoring and can contribute to serious complications, including hypertension, stroke and heart failure.
People who took Zepbound had an average of 27.4 fewer AHI events per our at 52 weeks, compared to an average reduction of 4.8 events per hour for the placebo. People who took Zepbound had an average of 30.4 fewer AHI events per our at 52 weeks, compared to an average reduction of 6 events per hour for the placebo.
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