Eli Lilly said its highly popular weight loss drug Zepbound showed the potential to treat patients with the most common sleep-related breathing disorder in two late-stage clinical trials.
The results are an early sign of hope for the estimated 80 million patients in the U.S. suffering from OSA, which refers to interrupted breathing during sleep due to narrowed or blocked airways. Around 20 million of those people have moderate-to-severe forms of the disease, but 85% of OSA cases go undiagnosed, according to Eli Lilly., loud snoring and can contribute to serious complications, including hypertension, stroke and heart failure.
Zepbound led to an average AHI reduction of 25.3 events per hour at 52 weeks, regardless of whether a patient discontinued the treatment. That compares to an average reduction of 5.3 events per hour for the placebo. Eli Lilly's drug led to an average AHI reduction of 29.3 events per hour at 52 weeks, regardless of whether a patient discontinued the treatment. That compares to an average reduction of 5.5 events per hour for the placebo.
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Eli Lilly’s weight loss drug Zepbound found to reduce sleep apnea, company saysBerkeley Lovelace Jr. is a health and medical reporter for NBC News. He covers the Food and Drug Administration, with a special focus on Covid vaccines, prescription drug pricing and health care. He previously covered the biotech and pharmaceutical industry with CNBC.
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