By Bhavana KunkalikarSep 27 2022Reviewed by Aimee Molineux In a recent study published in the Diabetes Care journal, researchers assessed the relationship between incident type 1 diabetes and recent coronavirus disease 2019 Infection.
Early in the epidemic, Public Health Scotland established the Rapid Epidemiological Analysis of Comorbidities and Treatments as Risk Factors for COVID-19 in Scotland study as a matched case-control study comprising all diagnosed SARS-CoV-2 infections in Scotland having up to 10 control individuals per case. These control individuals were matched for age, gender, and general practice.
The first SARS-CoV-2 positive polymerase chain reaction test in the Electronic Communication of Surveillance in Scotland database, which records all PCR testing for COVID-19 countrywide, was used to define SARS-CoV-2 infection. Some persons with a confirmed clinical diagnosis of COVID-19 who had never tested SARS-CoV-2 positive were included in the REACTSCOT cases.
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Long-term neuromuscular consequences of SARS-Cov-2 and their similarities with myalgic encephalomyelitis/chronic fatigue syndrome: results of the retrospective CoLGEM study - Journal of Translational MedicineBackground Patients with long-COVID often complain of continuous fatigue, myalgia, sleep problems, cognitive dysfunction, and post-exertional malaise. No data are available on EMG recording of evoked myopotentials (M-waves) or exercise-induced alterations in long-COVID patients, providing evidence of muscle membrane fatigue. Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) develops in more than half of patients after an infectious disease, particularly viral diseases. A large proportion (around 70%) of these patients have neuromuscular disorders with M-wave alterations during and after exercise. Our hypothesis was that M-wave alterations would be also found in long-COVID patients, in association with neuromuscular symptoms, similar to ME/CFS. Methods This retrospective observational ColGEM (Covid LonG Encéphalomyelite Myalgique) study compared 59 patients with long-COVID and 55 ME/CFS patients with a history of severe infection who presented before the COVID pandemic. All of these patients underwent the same protocol consisting of a questionnaire focusing on neural and neuromuscular disorders and M-wave recording in the rectus femoris muscle before, during, and 10 min after a progressive cycling exercise. Maximal handgrip strength (MHGS) and maximal exercise power were also measured. The frequency of symptoms and magnitude of M-wave changes in the two groups were compared using non-parametric and parametric tests. Results The frequency of fatigue, myalgia, sleep problems, cognitive dysfunction, and post-exertional malaise as well as the magnitude of exercise-induced M-wave alterations were the same in the two groups. By contrast, digestive problems were less present in long-COVID. M-wave alterations were greater in ME/CFS patients as in those with long-COVID when the highest muscle strength and highest exercise performance were measured. Conclusions These high clinical and biological similarities between long-COVID and ME/CFS support the hypothesis that S
Source: BioMedCentral - 🏆 22. / 71 Read more »
Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against OmicronThe findings of a new Swedish study posted to the Preprints with The Lancet* server found that two COVID-19 vaccine doses provided effective long-term protection against infection before Omicron, but less protection against Omicron infection (dropping to 43% by week four and no protection by week 14).
Source: NewsMedical - 🏆 19. / 71 Read more »
Post-recovery COVID-19 and incident heart failure in the National COVID Cohort Collaborative (N3C) study - Nature CommunicationsThe relationship between post-recovery COVID-19 and incident heart failure has not been investigated at scale. Here, the authors use electronic health records for ~600,000 patients in the US and find a higher rate of post-discharge incident heart failure in those hospitalised with COVID-19 than without. NatureComms SARSCoV2 primaryhealthcare The risk of heart failure after hospitalization with COVID-19 is reduced by prescribing sunlight, restoring gut microbiome health with probiotics and access to Mediterranean meals and improving nocturnal melatonin amplitude and volume. .
Source: medical_xpress - 🏆 101. / 51 Read more »
Barbados drops all Covid entry rulesThe lifting of Covid entry requirements are expected to boost tourism to the popular Caribbean holiday destination during the winter season
Source: TheVoiceNews - 🏆 119. / 51 Read more »
The UAE Is Scrapping Its Covid Mask Requirements After 2½ YearsThe ruling officially applies to just the UAE capital Abu Dhabi, but the country’s six other emirates, including Dubai, are expected to follow suit.
Source: NECN - 🏆 20. / 71 Read more »