Managing diabetes with probiotics and synbiotics

By Dr. Sanchari Sinha Dutta, Ph.D.Apr 16 2024Reviewed by Benedette Cuffari, M.Sc. In a recent study published in the journal Clinical Nutrition , researchers reviewed data obtained from randomized clinical trials that have investigated the effects of prebiotics and synbiotics on glycemic control in patients with type 1 and type 2 diabetes .

Despite recent advancements in anti-diabetic treatments, a significant proportion of patients continue to experience suboptimal glycemic control. Among various novel strategies for glycemic control, targeting the gut microbiota through probiotics and other therapeutics has been proposed as a novel approach to managing diabetes.

Study design For the current review, researchers utilized various electronic databases to identify relevant RCTs that included adult patients with diabetes who were being treated with probiotics or synbiotics in addition to their specific anti-diabetic treatments. RCTs that compared these interventions with other treatments, placebo, or standard diabetic treatment in the context of glycemic control were included in the meta-analysis.

The sub-group analysis demonstrated that the efficacy of tested interventions varies between the type of microbial strains used and between countries. Regarding the different types of bacterial species used in probiotic formulations, certain Lactobacillus strains and Bifidobacterium lactis were associated with pronounced effects, especially in multispecies formulations. Thus, the therapeutic efficacy of probiotic interventions for managing diabetes may be strain-specific.

Source: Healthcare Press (healthcarepress.net)

Probiotics Efficacy Fasting Glucose Hba1c Insulin Nutrition Prebiotics Probiotic Type 1 Diabetes

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