By Vijay Kumar MalesuMay 27 2024Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the journal Psychiatry Research, a group of researchers evaluated the effects of a ketogenic diet on metabolic and psychiatric health in individuals with schizophrenia or bipolar disorder with existing metabolic abnormalities.
Background Millions worldwide suffer from severe mental illnesses, such as schizophrenia and bipolar disorder . Current treatments often lead to resistance or metabolic side effects, causing nonadherence. Traditional neuroleptics can reduce life expectancy despite benefiting long-term mortality in schizophrenia. The KD, effective in treating epilepsy, offers an alternative fuel source for the brain, reducing neuronal excitability and inflammation.
The KD prescribed consisted of 10% carbohydrates, 30% protein, and 60% fat, aiming for blood ketone levels between 0.5-5 mM. Compliance was monitored based on ketosis levels. Blood samples were analyzed for metabolic markers, and vital signs, body composition, and psychiatric evaluations were recorded at baseline, two months, and four months. Remote participants self-reported data and attended local facilities for assessments.
Source: Healthcare Press (healthcarepress.net)
Diet Ketogenic Diet Mental Health Schizophrenia Blood Brain Epilepsy Life Expectancy Metabolic Syndrome Mortality Psychiatry Research Syndrome
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