US investigating mysterious liver disorder in children as cases climb

At least six US states are reporting confirmed or suspected cases of an unexplained, severe liver disorder in children that’s been spotted in countries around the globe.

More than 160 cases of severe paediatric hepatitis, or liver inflammation, in children without existing health issues have been reported from about a dozen countries, including the UK, Canada and Japan. The disorder has been seen mainly in children younger than 10 and has left a few needing liver transplants. Researchers are probing links to infection with adenoviruses, a family of pathogens that more commonly cause cold-like symptoms, as well as Covid-19.

“It’s still a mystery,” Fauci said. “It seems to be associated with adenovirus, but it isn’t a slam dunk.” Because the cases are appearing in clusters, it’s likely they’re caused by a viral organism, according to Tina Tan, a paediatric infectious disease physician at Lurie Children’s Hospital in Chicago and a member of the Infectious Diseases Society of America , but experts are still largely in the dark about which virus that could be.

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