Zepbound weight loss drug shortage has no immediate end in sight, Eli Lilly says

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Berkeley Lovelace Jr. is a health and medical reporter for NBC News. He covers the Food and Drug Administration, with a special focus on Covid vaccines, prescription drug pricing and health care. He previously covered the biotech and pharmaceutical industry with CNBC.

Despite Eli Lilly’s assurances about an ample supply of its new weight loss drug Zepbound, the company is now facing widespread shortages just months after its approval. While the drugmaker is working to resolve the issue, a quick fix is unlikely, it says, with no immediate end to the shortage in sight. The Food and Drug Administration approved Zepbound in November, introducing a new competitor to Novo Nordisk’s blockbuster weight loss drug Wegovy.

Christopher McGowan, a gastroenterologist who runs a weight loss clinic in Cary, North Carolina, said that patients who miss more than two weeks of a weight loss drug may be forced to start their treatment over again at the lowest dose and then gradually increase over several weeks, in order to reacclimate to the side effects. Starting over can be “immensely disruptive” and “demoralizing” for patients who have successfully lost weight on the drugs, he said.

 

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