The coronavirus may cause fat cells to miscommunicate, leading to diabetes

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COVID-19 patients with high blood sugar had low levels of a hormone made by fat.

, including many, like Sullivan, who were not previously diabetic, cardiologist James Lo and colleagues reported November 2 in. About 91 percent of the intubated COVID-19 patients had high blood sugar, as did almost 73 percent of people who died of the disease, the researchers reported.

Such sky-high levels of blood sugar were associated with a 15 times higher risk of intubation and 3.6 times higher risk of death compared with people with the disease who had normal blood sugar levels, Lo and colleagues found.Notes Pajvani, “we don’t know if the high blood sugar is causal of the bad outcome or reflective of the bad outcome.” Still, he and other doctors aren’t totally surprised by the connection between COVID-19 and high blood sugar, or hyperglycemia.

“The outlook was still bad, just not as bad in the group with ARDS and COVID, which is surprising,” says Ralph DeFronzo, an endocrinologist and chief of the diabetes division at the University of Texas Health Science Center at San Antonio, who was not involved with Lo’s study.Exactly what sends blood sugar soaring and causes diabetes in COVID-19 patients has been a mystery.

. Levels of several other hormones produced by fat cells were also out of whack, the researchers found. Experiments by other researchers have also indicated that SARS-CoV-2, the virus that causes COVID-19, can replicate in human fat, also known as adipose tissue, says Jose Aleman, an endocrinologist at the New York University Grossman School of Medicine. That’s yet another clue that fat is involved in severe disease.of 10 of 18 men who died of COVID-19, researchers in Germany report January 4 in. All 10 of the men with coronavirus in their fat were overweight or obese.

But the conclusion is not a slam dunk, Pajvani says. “This is an example of very good research done in very difficult settings.” But because the study looked back a group of patients, but didn’t match their characteristics and limit other variables from the beginning, the work can’t definitively show the cause of COVID-related diabetes. “This gives us a great hint of the type of study to do,” he says.

 

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Perhaps vice versa also true?

31-166% is a huge margin.

What percentage chart being used here? Is 166% 2.66 times more likely?

“type 1 diabetes in children younger than 18 years-old and type 2 diabetes in adults.” This is not really how type 1 and 2 diabetes are differentiated and the CDC report doesn’t say it either

PaoloShirasi Will probably turn out to be causation vs correlation issue.

They cut your legs off if this goes bad.

Diabetes are mostly genetically related matters. If CD19 does this in some then this virus is specifically attacking certain genetic & hereditary immune systems. Let's find out!

Caused by Covid or was it already that high when they got the virus? Wouldn't be surprised either way with how some people eat.

Any one over the age of 45 has a drastic increase of the chances of developing diabetes.....Sars-Cov-2 or not. science

Covid 19 is bioengineered weapon.

SouthcoastHlth

This!!!!!

Cart before the horse message here. Should report for bogus info.

It could be Killings some fat cells. But no, it makes them worse...

Yeah yeah.....is that for people who are not diabetic

Thanks for posting. So important to know patients who have experienced Covid have much higher chance of becoming Diabetic after,even if not diabetic before disease.Also, triglycerides may be elevated. So doctor's should monitor,for both blood sugar and triglyceride levels after.

Good research ❤️

“Obesity is often associated with inflammation in fat and other tissues. Coronavirus infection may make that inflammation worse, tipping the scales toward messed-up hormone production and eventual diabetes”

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