Fat genes that make people up to six times more likely to become obese in adulthood have been discovered by scientists.
The genes were also found to be associated with an increased risk of non-alcoholic fatty liver disease and type 2 diabetes. However, while both BSN and APBA1 encode proteins found in the brain, they are not currently known to be involved in the leptin-melanocortin pathway. Professor John Perry, a study author and MRC Investigator at the University of Cambridge, explained: “These findings represent another example of the power of large-scale human population genetic studies to enhance our understanding of the biological basis of disease.
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