Pfizer Starts Phase III Clinical Trials of mRNA Flu Vaccine

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The drug company Pfizer says it has started giving its experimental mRNA influenza vaccine to some of the 25,000 adults taking part in stage III clinical trials for the vaccine.

“The flexibility of mRNA technology and its rapid manufacturing could potentially allow better strain matches in future years, and in a pandemic influenza situation, mRNA technology could allow rapid, large-scale manufacturing of vaccines,” Pfizer said in a news release.

“Moderna is proactively preparing for a confirmatory efficacy study for mRNA-1010 as early as the 2022/2023 Northern Hemisphere influenza season, if needed,” the release said. The CDC estimates that the flu resulted in 12,000 to 52,000 deaths and 140,000 to 710,000 hospitalizations each year between 2010 and 2020, with a greater impact on racial and ethnic minority groups.

 

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There are so many possible scenarios with artificially engineering RNA that the best computer modeling can not predict all the negative reactions.

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