'One ring to rule them all': How actin filaments are assembled by formins

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Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing filament. Furthermore, the scientists elucidated the reasons for the different speeds at which the different formins promote this process.

'One ring to rule them all': How actin filaments are assembled by formins." ScienceDaily. ScienceDaily, 16 April 2024. <www.sciencedaily.comMax Planck Institute of Molecular Physiology. . 'One ring to rule them all': How actin filaments are assembled by formins.Max Planck Institute of Molecular Physiology."'One ring to rule them all': How actin filaments are assembled by formins." ScienceDaily. www.sciencedaily.

Actin filaments are dynamic protein-fibers in the cell built from single actin proteins. Many cellular functions, including cell movement, are regulated by constant filament assembly and disassembly. ... When an actin filament bends during cell movement, older actin deforms differently than newer actin, allowing regulatory proteins to tell the two states ...

Actin filaments are protein fibers that make up the internal skeleton of the cell. As active elements of our cells, actin filaments support the cell's fusion, movement and are involved in many ... Actin filaments have several important functions inside cells. For one, they support the cell membrane by binding to it. However, scientists did not know exactly how the actin interacts with the ...

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