Once a Covid hotspot, Italian village now intrigues researchers with 'super-immune' cases

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Covid-19 “super-immune” people seem to be in a high concentration in an Italian village. Researchers want to know why.

Italian soldiers patrol by a check-point at the entrance of the small town of Vo' Vecchio, situated in the red zone of the Covid-19, northern Italy, on Feb. 24, 2020.LONDON — Paola Bezzon thought her sniffles in December were just a seasonal cold until a serology test months later found coronavirus antibodies in her blood.

Bezzon, 68, lives in Vo', a town of about 3,300 people west of Venice, which became one of the first cities outside China to experience a Covid-19 outbreak — and. Researchers, hoping to understand the virus and the human immune response to it, arrived shortly after. Two centuries later, the ever-expanding commerce and military forces of Venice reclaimed marshy and unproductive land 40 miles to its west. Vo' was born, but it remained largely unknown — more a place to travel through to and from Venetian ports and the Italian inland.

A man from Vo' who died at the hospital in Schiavonia was the first European COVID-19 death registered on Feb. 12, 2020.in other parts of the world, it's rare for people's antibodies to increase instead of dissipate."A vaccine is an artificial exposure to a pathogen," Lavezzo said."It's like promoting the immune memory of those who get vaccinated, so next time they get in contact with the virus, their response can be faster and stronger.

Tents are set up outside a hospital in Schiavonia after Italy's first Covid-19 cases were identified nearby, Feb. 12, 2020.The local council telephone line dedicated to assisting the population was getting overwhelmed by threatening calls. Of 3,300 people in Vo', around 2,800 participated in the rounds of testing. Raffaella Frasson, 53, will show up for the next one, as well, to see whether, as one of the super-immunes, she continues to have elevated antibody levels.

 

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Easy. They’re all inbred cousins, an ancestor of whom happened, purely by chance, to have the magic gene.

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