“Genetic background contributes to the amount of physical activity needed to mitigate obesity. The higher the genetic risk, the more steps needed per day,” said senior researcher Douglas Ruderfer, director of the Center for Digital Genomic Medicine at Vanderbilt University Medical Center in Nashville, Tenn.
Obesity increased 43% among people with the highest genetic risk scores for obesity, but only by 13% among those with the lowest risk, researchers found. Further, people with high genetic risk and BMIs between 22 and 28 needed to walk an additional 3,460 to 6,350 steps per day to have a risk comparable to folks with the least genetic predisposition to obesity.
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