Not just “leuko” after all: Epithelial leukotriene production in type 2 immunity

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Growing evidence shows tuft cells are important producers of leukotrienes, lipid moderators of type 2 immune responses. Read more in this SciImmunology Focus article:

M. de Los Reyes Jiménez, A. Lechner, F. Alessandrini, S. Bohnacker, S. Schindela, A. Trompette, P. Haimerl, D. Thomas, F. Henkel, A. Mourão, A. Geerlof, C. P. da Costa, A. M. Chaker, B. Brüne, R. Nüsing, P.-J. Jakobsson, W. A. Nockher, M.

J. Feige, M. Haslbeck, C. Ohnmacht, B. J. Marsland, D. Voehringer, N. L. Harris, C. B. Schmidt-Weber, J. Esser-von Bieren, An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products.

 

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