Moderna Launches Clinical Trials for HIV Vaccine

The first vaccinations were given Thursday at George Washington University School of Medicine and Health Sciences in Washington, DC, the company said in a

. Phase I trials will also be run at the Hope Clinic of Emory Vaccine Center in Atlanta, the Fred Hutchinson Cancer Research Center in Seattle, and the University of Texas Health Science Center at San Antonio.reported. A booster shot to work with the HIV vaccine is also being studied.’s attempts to destroy it. Scientists have not been able to develop a vaccine, though they have made advancements in treatments, such as long-acting injectables for pre- and post-exposure prevention and treatment.

The release said 56 healthy HIV-negative adults are taking part in the clinical trial, with 48 getting one or two doses of the mRNA vaccine and 32 also getting the booster. Eight people will just get the booster. All of them will be monitored for up to 6 months after receiving a final dose. The immunogens -- antigens that elicit an immune response -- that are being tested were developed by the International AIDS Vaccine Initiative and Scripps Research. They will be delivered using the same messenger RNA technology in Moderna’s successful COVID-19 vaccine, the news release said.

About 1.2 million people in the United States had HIV at the end of 2019, according to the CDC, with more than 36,000 people being diagnosed in 2019.“We are tremendously excited to be advancing this new direction in HIV vaccine design with Moderna's mRNA platform,” Mark Feinberg, MD, president and CEO of IAVI, said in the news release.

It seems WebMD has a different definition for the word 'successful'. It is not successful if it does not stop transmission, contagion and death.

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