Many Drugs Associated With SJS-TEN in Children, WHO Data Analysis Show

Antiepileptic and anti-infectious agents were the most common drugs associated with Stevens-Johnson syndrome /toxic epidermal necrolysis in children in an analysis of a World Health Organization database.SJS and TEN are rare, life-threatening mucocutaneous reactions mainly associated with medications, but large pharmacovigilance studies of drugs associated with SJS-TEN in the pediatric population are still lacking.

They analyzed drugs reported as suspected treatments, and for each molecule, they performed a case–non-case study to assess a potential pharmacovigilance signal by computing the information component .Overall, 165 drugs were associated with a diagnosis of SJS-TEN; antiepileptic and anti-infectious drugs were the most common drug classes represented.

Source: Entertainment Trends (entertainmenttrends.net)

Children Child Childhood Pediatrics Kids Pain Management Pediatric Dermatology Nonsteroidal Anti-Inflammatory Drugs Nsaids NSAID Nonsteroidal Anti-Inflammatory Drugs Nonsteroidal Anti-Inflammatory Agents Antibiotics Adverse Effects Side Effects Antifungal Drug Reaction Hospitals Stevens-Johnson Syndrome Fungal Infection Vaccine Vaccines

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