Life histories of myeloproliferative neoplasms inferred from phylogenies - Nature

. Time-based phylogenetic trees. Different coloured branches identify separate clades alongside light blue wild type colonies. The vertical axis represents age post conception with treatment received alongside. Driver mutations are depicted in the middle of the branches but may have occurred at any point between the start and end of the branches.

Extended Data Fig. 7 legend: Aberrant cell fractions in bulk blood samples and validation of selection estimates.. Plots showing aberrant cell fraction in colonies and bulk longitudinal mature blood cell samples. Colony samples were derived from peripheral blood or bone marrow mononuclear cells. Bulk mature blood cell samples comprised mostly peripheral blood granulocytes and occasionally, bone marrow derived granulocytes or mononuclear cells , and whole blood .

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