"We've identified specific genetic signatures in the gut microbiome that were predictive of weight loss response in a small cohort of patients following a healthy lifestyle intervention," says Gibbons, assistant professor at the Institute for Systems Biology in Seattle.Differences in 31 functional genes emerged from the gut microbiome among 48 people who lost 1% or more of their weight each month compared with 57 others whose weight remained the same.
"By understanding these functional patterns, we may one day be able to engineer resistant microbiomes to be more permissive to weight loss," Gibbons said. Kahleova agreed."These findings expand our understanding on the specific features of the gut microbiome that play a role in weight loss," she said.— to include more of the gut bacteria that facilitate weight loss?
It could be too soon for such interventions, Gibbons said."It is still very difficult to rationally engineer your gut microbiome."donor may be able to flip low-More research is required, however, to understand whether or not these fecal microbial transplant-flipped individuals are also more capable of weight loss, he added.
Beyond that,"I can't give any specific recommendations, other than that [people] should eat more fiber-rich,"Also, prepare your own meals, rather than relying on sugar and sodium-rich processed foods," Gibbons said.
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