FDA clears AstraZeneca’s COVID-19 antibody treatment for immunocompromised

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The Food and Drug Administration authorized the first injectable monoclonal antibody cocktail for long-term prevention of COVID-19 among people with weakened

for long-term prevention of COVID-19 among people with weakened immune systems before they have been exposed to the coronavirus.Wednesday for AstraZeneca’s antibody cocktail, Evusheld, for what is known as pre-exposure prophylaxis, or PrEP, against COVID-19.

The AstraZeneca therapy involves getting preventive injections as often as every six months. According to a large placebo-controlled clinical trial, the cocktail is about 83% effective at preventing symptomatic disease during such an interval.of the coronavirus — which is spreading in 57 countries, including the U.S.— might affect the efficacy of the monoclonal antibody therapy.

Evusheld as PrEP, he said, “provides a healthy load of antibodies for the 40% to 80% of the immunosuppressed who have very poor antibody responses following SARS-CoV-2 vaccination.”

 

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