FDA Approves ide-cel for Adults with Relapsed or Refractory Multiple Myeloma

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FDA,Ide-Cel,Multiple Myeloma

The FDA has approved ide-cel, a chimeric antigen receptor (CAR) T-cell therapy, for adults with relapsed or refractory multiple myeloma after two or more prior lines of therapy. The approval expands the therapy's indications to earlier lines of treatment after exposure to other main therapy classes.

for adults with relapsed or refractory multiple myeloma after two or more prior lines of therapy, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 monoclonal antibody.

Approval was based on the KarMMa-3 trial, in which 254 patients were randomly assigned to ide-cel and 132 to investigators' choice of standard regimens, consisting of combinations of

FDA Ide-Cel Multiple Myeloma CAR T-Cell Therapy Relapsed Refractory Therapy

 

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