Eli Lilly's weight loss drug reduces sleep apnea, study shows

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Eli Lilly noted that tirzepatide reduced sleep apnea severity by up to nearly two-thirds in adults that have both obstructive sleep apnea and obesity.

Eli Lilly's weight loss-related drug Zepbound could potentially be used to reduce the severity of sleep apnea in adults with obesity, according to a recent study. Results of a phase three clinical trial, published Wednesday, showed that injections of the drug, either 10 mg or 15 mg, "significantly reduced the apnea-hypopnea index compared to placebo.

The adults who were evaluated were not on positive airway pressure therapy, which uses a machine to pump air under pressure into the lungs, for 52 weeks during the trial. Currently, tirzepatide is approved for chronic weight management and sold under the brand name Zepbound. It's also approved for treatment of Type 2 diabetes and sold under the brand name Mounjaro.

 

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