To test LTP-like neuroplasticity, Brüchle et al. used a combination of transcranial magnetic stimulation protocols, short-interval intracortical inhibition , and paired-associative stimulation describedThe researchers found that higher baseline BDI-II scores were correlated with lower levels of neuroplasticity.
However, she emphasizes that these correlative findings do not imply causation."We cannot say to what extent the change in symptoms and the brain's ability to change are causally linked based on this data," Rosenkranz noted.
The latest"exercise and depression" research identifies a correlation between regular physical activity, improved depressive symptoms, and restored neuroplasticity in patients with MDD. More research is needed to identify causal links and establish the clinical relevance of neuroplasticity-enhancing exercise interventions for treating major depressive disorders.
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