Delirium Linked to a Threefold Increased Risk for Dementia

Delerium is tied to a significantly increased risk for dementia and death in older adults , with men at particular risk, new research showed., with each additional episode linked to a further 20% increase in dementia risk. The association was strongest in men."We have known for a long time that delirium is dangerous, and this provides evidence that it's even more dangerous than perhaps we had appreciated," study investigator Emily H.

Investigators matched patients in the delirium group to patients with no delirium according to characteristics with potential to confound the association between delirium and risk for dementia, including age, gender, frailty, reason for hospitalization, and length of stay in hospital and intensive care.

Among patients with at least one episode of delirium, the rate of incident dementia was 3.4 times higher than in those without delirium. After accounting for the competing risk for death, incident dementia risk remained three times higher among the delirium group .Sex Differences In addition to its large size, long follow-up, and close matching, what sets this new study apart from previous research is it accounted for the competing risk for death, said Gordon.

Study limitations included the potential for residual confounding from unmeasured variables in the matching criteria. Delirium and dementia diagnoses depended on clinical coding of medical information recorded in the administrative dataset, and under-coding of dementia during hospitalization is well-recognized.

Dementia Hospitals Geriatrics Elder Care Geriatric Medicine Older Adults Seniors Senior Citizens Elderly Intensive Care Unit ICU - Intensive Care Unit

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