Professor of Medicine, Columbia University Irving Medical Center; Chairman of Medicine, Eugene Sayfie Chief of Cardiology, Columbia University Division of Cardiology at Mount Sinai, Mount Sinai Medical Center of Florida, Miami Beach, FloridaTricia Ward:
What is chelation? A chelating agent is a chemical compound that has a particular shape with a pocket. It's like a baseball mitt with a magnet in it. The one that we're talking about is ethylenediaminetetraacetic acid , or edetate disodium, which is the US Food and Drug Administration designation. , which ran from 2003 until 2012. This study has exactly the same design.
We had this surprise result with an 18% relative risk reduction in all-comers with a prior heart attack that was statistically significant, and a spectacular 41% relative risk reduction in the patients who had diabetes. The FDA said,"Well, this is very interesting. Why don't you do it again?" started. The first patient was randomized in 2016. We randomized 1000 patients.
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