A hope for HIV patients: An infected woman turns virus-free on her own

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An Argentinian woman whose partner died of AIDS and was also HIV-positive herself, has cleared her body of the virus, raising the possibility of a ‘sterilising cure’

notes “Fewer than 1% of people living with HIV are able to control viral replication to below the limits of detection by commercial assays without antiretroviral therapy .”

Blankson goes on to say that these patients “are called ‘elite controllers’ or ‘elite suppressors,’ and they represent a model of a cure for HIV-1. Blankson does mention a caveat: “However, it has not always been clear whether they are models of a functional cure, where replication-competent virus remains but is controlled by host factors , or a sterilising cure, where the virus is eradicated by the host .”, titled “A Possible Sterilising Cure of HIV-1 Infection Without Stem Cell Transplantation” speaks of the Esperanza patient as an elite controller who may have been a model of a sterilising cure.

“What happened is unique,” Steven Deeks, an HIV researcher at the University of California at San Francisco, who was not involved in the study tells the. “It’s not that she’s controlling the virus, which we do see, but that there’s no virus there, which is quite different.”from UNAIDS, “37.7 million [30.2 million–45.1 million] people globally were living with HIV in 2020.

HIV has no known cure, but can be treated by a cocktail of drugs, and in the case of three people, eliminated altogether through stem cell transplants to cure their cancer.

 

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