-positive person whose body might have naturally cleared the infection -- sparking hope that studying such exceedingly rare events will help lead to a cure.
The woman, whom the researchers call the Esperanza patient , is the second known person to have potentially cleared HIV infection naturally. If the two patients have achieved a natural cure, the big question is: How? And can that 'how' be turned into a cure for others?The Esperanza case, reported in the Nov. 16 issue ofand the San Francisco case were discovered through ongoing research of so-called"elite controllers."
That's where the Esperanza and San Francisco patients stand out. The researchers have found no evidence of latent HIV reservoirs in either patient. Hopefully, that will shed light on the mechanisms that allow the patients such exceptional HIV control. In other words, the viral genetic material is sequestered far away from the genes a blood cell uses to make proteins. That suggests those infected cells are less able to churn out copies of HIV."Exceptional" controllers are clearly even rarer than elite controllers. How rare is unknown.
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