By Tarun Sai LomteOct 31 2023Reviewed by Lily Ramsey, LLM In a recent study published in JAMA Network Open, researchers examined maternal depressive symptoms in diverse observational cohorts.
Studies indicate a higher incidence of maternal clinical depression post-childbirth. Nevertheless, these studies lacked prospective longitudinal analyses to delineate the onset time. Participants were recruited during pregnancy or pre-conception. The team harmonized data on maternal depressive symptoms from pregnancy through two years after childbirth.
The team derived a latent depression trait estimate per participant for each time point, providing a trajectory of depressive symptoms over time. Participant groups having similar trajectories were identified using K-means clustering. Consistently, this sub-group showed a stable trajectory of depressive symptoms throughout the perinatal period.
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