Lots of great things come with age: wisdom, self-awareness, possession of some fabric softener. But some additions, like grey hair, might not be everyone’s favourite signs of growth.discovered what causes greying hair – and what you might be able to do to reverse it.that the stem cells linked to grey hairs appear to work in a different way to other stem cells. The stem cell is the first to fail in humans and mice – leading to grey hairs in both.
Melanin is present in human and animal skin to varying degrees, and is responsible for your unique eye, hair and skin colour, according toThe study found melanocyte stem cells move through your hair follicles. And these different compartments of your hair might have different proteins that kick off different developmental stages for the cell.that McSCs sort of toggle between life stages as they move through your hair .
Instead, the McSCs tend to stay in one compartment of your hair called the hair follicle bulge when you get older. And actually, rather than over-maturing the McSCs, this section of your hair prevents them from developing in the first place. So they remain grey and don’t develop any colour – a bit like a blank piece of paper before you print on it.
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Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review - BMC Palliative CareBackground Psychological distress is common in patients with cancer; interfering with physical and psychological wellbeing, and hindering management of physical symptoms. Our aim was to systematically review published evidence on non-pharmacological interventions for cancer-related psychological distress, at all stages of the disease. Methods We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The review was registered on PROSPERO (CRD42022311729). Searches were made using eight online databases to identify studies meeting our inclusion criteria. Data were collected on outcome measures, modes of delivery, resources and evidence of efficacy. A meta-analysis was planned if data allowed. Quality was assessed using the Mixed Methods Appraisal Tool (MMAT). Results Fifty-nine studies with 17,628 participants were included. One third of studies included mindfulness, talking or group therapies. Half of all studies reported statistically significant improvements in distress. Statistically significant intervention effects on distress were most prevalent for mindfulness techniques. Four of these mindfulness studies had moderate effect sizes (d = -0.71[95% CI: -1.04, -0.37] p | 0.001) (d = -0.60 [95% CI: -3.44, -0.89] p | 0.001) (d = -0.77 [CI: -0.146, -1.954] p | 0.01) (d = -0.69 [CI: -0.18, -1.19] p = 0.008) and one had a large effect size (d = -1.03 [95% CI: -1.51, -0.54] p | 0.001). Heterogeneity of studies precluded meta-analysis. Study quality was variable and some had a high risk of bias. Conclusions The majority of studies using a mindfulness intervention in this review are efficacious at alleviating distress. Mindfulness—including brief, self-administered interventions—merits further investigation, using adequately powered, high-quality studies. Systematic review registration This systematic review is registered on PROSPERO, number CRD42022311729.
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BBC - The Latest News from the UK and Around the World | Sky News'If the alleged victim doesn't harbour any complaints, it's not in the best interest of the police to pursue criminal charges' says lawyer Matthew Gill on the investigation of the BBC presenter accused of paying a teen for sexually explicit pictures.
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Ohio - The Latest News from the UK and Around the World | Sky NewsBodycam footage shared by the Ohio State Highway Patrol shows a state trooper stopping traffic on a busy highway to let a family of geese cross the road. Read more:
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Joe Biden - The Latest News from the UK and Around the World | Sky NewsThe US President jumped in to make the comment after the Ukrainian president was asked 'how soon after the war' with Russia would he like Ukraine to be part of NATO. Read more 👉
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Onana could fall foul of 'no d***heads' policy but stats suggest he's what Man United needSome red flags may have been raised by Manchester United bosses, but it’s a risk they are willing to take. United and Inter Milan are close to agreeing the transfer of the goalkeeper, which w…
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Live news: Berkshire Hathaway agrees $3.3bn deal for 50% stake in Cove Point LNG plant\n\t\t\tExpert insights, analysis and smart data help you cut through the noise to spot trends,\n\t\t\trisks and opportunities.\n\t\t\n\t\tJoin over 300,000 Finance professionals who already subscribe to the FT.
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