Study reveals metabolic syndrome's impact on brain volume and cognitive function

By Tarun Sai LomteReviewed by Lily Ramsey, LLMJun 24 2024 In a recent study published in Diabetes Care, researchers examined associations between metabolic syndrome and cognitive and neuroimaging outcomes in dementia-free adults.

MetS is recognized as a modifiable risk factor for cerebrovascular and cardiovascular diseases; thus, it could be an attractive target for disease prevention strategies. Besides, the global incidence of dementia has been increasing and is projected to triple in the next three decades. About the study The present study examined associations between MetS and cognitive and neuroimaging outcomes. They used data from the United Kingdom Biobank.

MetS was defined as the presence of at least three components: abdominal obesity, elevated blood pressure, elevated triglycerides, reduced HDL cholesterol, and elevated fasting blood glucose. Findings Overall, 37,395 participants were included; of these, 7,945 had MetS. The MetS group was more likely to be male, older, White, former smokers, less physically active, APOE-ε4 carriers, have less education and lower household income, and live in socioeconomically deprived areas.

Cognitive Function Metabolic Syndrome Syndrome Blood Blood Pressure Cardiometabolic Cholesterol Dementia Diabetes Education Glucose Imaging Lipoprotein Neuroimaging Obesity Pathology Public Health Vascular

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