Kidneys from genetically modified pig transplanted into brain dead human

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It could be the answer to a global organ shortage

The transplanted organs were able to carry out the functions of kidneys, scientists from the University of Alabama at Birmingham in the US report.According to the study, the kidneys continued working until 74 hours later.

Dr Locke, director of the Comprehensive Transplant Institute in the UAB’s Department of Surgery, said: “This game-changing moment in the history of medicine represents a paradigm shift and a major milestone in the field of xenotransplantation, which is arguably the best solution to the organ shortage crisis.

Some 10 genes were changed in this latest donor pig. Four were disabled pig genes, also known as knockouts, and six were human genes that were cloned into the pigs, also known as knock-ins. The pig kidneys were placed in the exact anatomic locations used for human donor kidneys, with the same attachments to the renal artery, renal vein and the ureter that carries urine from the kidney to the bladder.

Mr Parsons’s ex-wife, Julie O’Hara, said: “Jim would have wanted to save as many people as he could with his death, and if he knew he could potentially save thousands and thousands of people by doing this, he would have had no hesitation.

 

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