By Pooja Toshniwal PahariaNov 1 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Canadian Medical Association Journal, researchers evaluated age-stratified hospitalization and mortality risks from incident severe acute respiratory syndrome coronavirus 2 infections in British Columbia , Canada, during the SARS-CoV-2 Delta variant of concern and Omicron VOC predominance.
The British Columbia Centre for Disease Control performed eight population-level, cross-sectional SARS-CoV-2 seroprevalence surveys from March 2020 to August 2022. The derived IHRs and IFRs represented severe COVID-19-related outcome risk from incident infections during the predetermined inter-survey periods. COVID-19 was confirmed using nucleic acid amplification tests . The sample population included individuals presenting for blood draws at the LifeLabs diagnostic outpatient center.
Bayesian analysis was performed to estimate seroprevalence, adjusting for gender, health authorities, and age. Age-stratified infection hospitalization and fatality ratios were mostly below one percent and ≤0.1%. However, there were exceptions. Individuals aged between 70 and 79 years in the period between serosurveys 6.9 and 7.0 had an IHR and IFR of three percent and one percent, respectively.
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