Emerging investigator series: meta-analyses on SARS-CoV-2 viral RNA levels in wastewater and their correlations to epidemiological indicators

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Before test results, signs of COVID-19 are in water systems wustl

Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, USACentre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, Division of Microbial Ecology, University of Vienna, Vienna, AustriaDepartment of Civil, Structural and Environmental Engineering, University at Buffalo, Buffalo, NY, USADepartment of Computer Science and Engineering, Washington University in St. Louis, St.

The mean positivity across all studies was 0.68 . The mean viral RNA abundance was 5244 marker copies per mL . The Pearson correlation coefficients between the viral RNA levels and case prevalence were 0.28 for daily new cases or 0.29 for cumulative cases. The fraction analyzed accounted for 12.4% of the variability in the percentage of positive detections, followed by the case prevalence and sampling mode . Among observations with positive detections, the fraction analyzed accounted for 56.

 

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