COVID-19 survivors face sleep battles, with ARDS patients hardest hit, study finds

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A recent study in the 'Journal of Clinical Medicine' explored the long-term effects on sleep and circadian rhythms in COVID-19 survivors who experienced acute respiratory distress syndrome (ARDS).

By Dr. Priyom Bose, Ph.D.Oct 24 2023Reviewed by Benedette Cuffari, M.Sc. The rapid transmission of the severe acute respiratory syndrome coronavirus 2 led to the coronavirus disease 2019 pandemic. COVID-19 is primarily a respiratory disease that manifests a wide range of symptoms, from mild to severe.

Background SARS-CoV-2 infection has significantly increased global hospitalization rates, particularly the intensive care unit occupation rate. One previous study indicated that at least 5% of the global population had developed ARDS, which could cause respiratory failure and the need for intermittent mandatory ventilation support. These patients are also at a higher risk of developing renal, cutaneous, cardiovascular, and hematological disorders.

About the study The current prospective, observational cohort study investigated alterations in sleep health and circadian rest-activity rhythm in ARDS patients among COVID-19 survivors within 12 months of hospital discharge. The study cohort was classified into ARDS and non-ADRS groups. The ARDS group included SARS-CoV-2 patients who required mechanical ventilation during their ICU stay, whereas the non-ARDS group included COVID-19 patients with mild to moderate symptoms. The non-ADRS group did not require hospitalization for SARS-CoV-2 infection.

A seven-day wrist actigraphy test was performed, which provided a daily measure of total sleep time , time in bed , and sleep efficiency . The circadian function index was also measured. Over 91% of COVID-19 survivors experienced poor sleep quality 12 months after hospital discharge, about 50% of whom reported experiencing daytime sleepiness. About 59% of patients experienced insomnia.

 

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