candidate say early phase trials of their product suggest it is unlikely to cause a potentially harmful antibody-dependent enhancement of the disease.
The most common effects were mild pain, slight fatigue and redness at the point of injection, they said. The team began phase 2 trials of the product – involving 750 adults from southwest China’s Yunnan province – in June, and tests involving an over-60s group were ongoing, Ying Zhang, who co-authored the study, said in an interview.
According to Professor Jin Dong-yan, a molecular virologist at the Li Ka Shing Faculty of Medicine at the University of Hong Kong, the risk with new vaccines was their potential to trigger ADE, which effectively made the virus more harmful than it was before inoculation.
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