Vitamin D deficiency is not responsible for TB in children - study

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Vitamin D deficiency has long been considered a risk factor for TB in adults as it impairs the immune response to the TB bug, but a new study by UCT has found that low levels of the sunshine vitamin in children doesn’t make them susceptible to the illness

In the study, published in the Clinical Infectious Diseases journal, which tracked infants from birth to seven years, researchers found that though vitamin D levels were extraordinarily low in the majority of these children, there was no relationship between TB incidence and vitamin D deficiency.

Researchers followed about 774 infants in the Drakenstein Child Health Study cohort who had a vitamin D measurement between six and 10 weeks of age. Vitamin D levels were extraordinarily low with 81% of infants in the cohort defined as vitamin D deficient. They found a very high incidence of TB disease, among the seven-year-olds, the highest ever reported globally. This was the first study to examine the correlation of the deficiency in children.

People living in Cape Town are at greater risk of vitamin D deficiency because the long winters compromise the sunlight’s ability to synthesise vitamin D.

 

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