Pharma executives mix vaccines in bid to broaden immunity

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Research is still underway but study in Spain shows mixing vaccine types can boost antibodies

London — When it comes to their own health, some in the pharma industry aren’t waiting for governments to tell them they can mix two different Covid-19 vaccines.

After years of reading research on mixing vaccine types — known as heterologous prime-boosting — Morgon concluded that getting one dose of the AstraZeneca shot, which uses a harmless virus as a vector, and another from Moderna’s or Pfizer’s newer messenger RNA technology would pack the most punch. Broadening immunity has become especially important as variants show some ability to evade vaccines.

Early research appears to back the approach. A study of almost 700 people in Spain showed that those who received a second dose of Pfizer’s vaccine after a first Astra shot saw their neutralising antibodies climb sevenfold, significantly higher than those who had two Astra doses.

 

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