So, what are gain-of-function studies? Although the term is sometimes used broadly to refer to “gain-of-function” studies of proteins, in medical terms, it is associated with research on viruses. The goal of gain-of-function research is to create a virus with new properties that make it more pathogenic or more transmissible to humans.
This process can lead to the rapid generation of new viruses that are better adapted to humans, possibly changing their virulence and their ability to be transmitted between humans. This knowledge could make it possible for scientists to better predict the arrival of new pandemics. It could help scientists develop vaccines and treatments adapted to new infectious agents.However, the principle underlying gain-of-function research has been widely challenged over the past decade.Ron Fouchier and Yoshihiro Kawaoka’s research on the highly dangerous avian H5N1 influenza virus
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