Next crop of Covid-19 vaccine developers take more traditional route

While Novavax Inc has not yet produced a licensed vaccine, it is using similar purified protein technology and expects to start a late-stage US trial involving 30,000 volunteers in late November.

Other second-wave developers are making vaccines based on virus-like particles , which mimic the structure of the coronavirus but contain no genetic material from it. Medicago has yet to produce an approved vaccine, but has completed large-scale testing for a seasonal flu vaccine using this approach. It plans to begin mid-stage trials of its Covid-19 vaccine next month and aims to make up to 1 billion doses a year by 2023.

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