GroundUp: UCT professor’s research offers hope of treatment for sickle cell anaemia

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80% of babies born with sickle cell anaemia are in sub-Saharan Africa. The disease in which red blood cells get stuck in blood vessels affects oxygen supply to the body.

A study performed in Cameroon by a University of Cape Town professor may offer hope of treatment for people with sickle cell anaemia , a disease which affects hundreds of thousands in Africa.

Sickle cell anaemia is the most serious in a group of disorders known as sickle cell disease. It is an inherited red blood cell disorder in which there aren’t enough healthy red blood cells to carry oxygen throughout the body. It is caused by a mutation in a single gene, responsible for production of the protein, haemoglobin. Making up 70% of the content of red blood cells, haemoglobin is essential for transporting oxygen throughout the body.

“Among the 300,000 babies that are born with the condition every year, 80% are in sub-Saharan Africa,” says Wonkam. “It is, in essence, an African disease.” However, the same regions of sub-Saharan Africa are also home to SCA patients who are 50 or 60 years old.

 

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