Interlagos is an old-style circuit, with an exuberant local crowd likely to be giving Hamilton plenty of love, and Vettel is a three times winner there.
Hamilton and team mate Valtteri Bottas will be looking to carry momentum on to Abu Dhabi and into the winter break, with the Briton on 83 career wins and eager to close the gap on Michael Schumacher's all-time record of 91. Ferrari and Red Bull are also looking ahead, their second and third positions secure in the constructors' standings.
Further down the pecking order, the fiercest battle is between Renault, Racing Point and Toro Rosso. Renault are fifth and 18 points clear of Racing Point, who are only one point ahead of seventh-placed Toro Rosso.
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