AstraZeneca vaccine trial restarts in Japan

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Trials in the UK, Brazil, SA and India have already restarted, but US trials remain paused as regulators widen their probe

Bengaluru — Clinical trials of AstraZeneca and Oxford University's experimental Covid-19 vaccine have resumed in Japan, almost a month after being put on hold due to an illness of a British volunteer, while discussions with US authorities continue.

Global trials of the vaccine, called AZD1222 or ChAdOx1 nCoV-19, were put on hold on September 6 after a study participant fell ill with what was believed to be a rare spinal inflammatory disorder called transverse myelitis. AstraZeneca has called the halt a standard review procedure, and a document posted online by Oxford university last month stated the illness may not have been associated with the vaccine.

The US Food and Drug Administration broadened its investigation of the illness in the volunteer, and would look at data from earlier trials of similar vaccines developed by the same scientists, three sources told Reuters.

 

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