Young people are getting Botox to prevent wrinkles. Does it work?

noticed faint lines forming on her face. She decided to try something she had seen other young people recommend on social media: Botox.

Botulinum toxin is the active ingredient in brand-name treatments such as Botox, Dysport, Xeomin and Jeuveau. While botulinum toxin has been well studied for a variety of uses, there haven’t been large-scale clinical trials on its long-term use to prevent wrinkles. Evidence supporting it is largely anecdotal or based on small studies, often funded by companies that sell the drug.

As we age, the body produces less collagen, a protein that serves as the skin’s main structural component — it gives the skin its firmness. We also lose elastin — a protein that gives skin its elasticity. With less collagen and elastin, the skin becomes thinner and less elastic — meaning that wrinkle lines can become more apparent, said Smita Ramanadham, a plastic surgeon in Montclair, N.J.Botulinum toxin works by blocking nerve signals that tell our muscles to move or contract.

“If you start at 25 and stop at 40, it’s sort of like you’ve stopped the clock for 15 years,” she said. “You still have the advantage of all the time you did use it.”Anecdotal evidence from dermatologists and plastic surgeons indicates that Botox does delay the onset of wrinkles. William J. Binder, a facial plastic and reconstructive surgeon in Beverly Hills, Calif., who worked on both studies, said they were not able to control for other factors that could have contributed to skin appearance, such as sun exposure, weight, diet or lifestyle. But in his follow-up study, he noted that both twins reported using sunblock daily, led active lifestyles, stuck to a relatively healthy diet and did not smoke.

Source: Healthcare Press (healthcarepress.net)

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