World’s 1st AI-made lung disease drug gets phase 2 trial in US, China

In the labyrinth of medical research, where countless diseases lurk without a cure, a beacon of hope emerges INS018_055, heralds a new era in the battle against Idiopathic Pulmonary Fibrosis as it strides into Phase II clinical trials.Amidst the whirlwind of challenges in the medical field, thousands of diseases are without effective treatments despite numerous investments and extensive research efforts.

“We report phase I clinical trial data highlighting the safety and tolerability of our small-molecule inhibitor. This comprehensive approach was completed in roughly 18 months from target discovery to preclinical candidate nomination and demonstrates the capabilities of our generative AI-driven drug-discovery pipeline.” the scientists stated.

Leveraging their AI platforms, including PandaOmics and Chemistry42, researchers identified the protein TNIK as a promising antifibrotic target. They subsequently utilized generative AI to discover INS018_055, an optimal inhibitor to block TNIK. “To date, we have found that INS018_055 demonstrated safety and tolerability in healthy volunteers, providing a strong basis for further clinical studies in patients with IPF.

“It is important to note that these results require further assessment in phase II and III clinical trials to validate these promising findings.” the scientists concluded.LinkedIn post reveals Tesla’s 5G ambitions for its EVs, Optimus robotAirCar: BMW engine-powered European flying car tech sold to China

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