The Wlodarski Laboratory is seeking talented and enthusiastic candidates for our Lead Researcher or Scientist opportunity to take a key role in our Blue-Sky funded project PARADIGM.), to directly address blood disorders caused by rare genetic mutations, with the long-term goal of developing individualized genome-editing medicines to cure inherited monogenic bone marrow failure disorders.
PARADIGM, supported by $5 million in institutional Blue Sky funding, aims to develop novel genome editing tools and establish preclinical models to test safety and efficacy of genome editors to cure BMF disorders.. He is a world-leading expert in inherited bone marrow failure disorders and his highly productive and collaborative continues to advance the field as documented by their recent discovery of a new genetic disorder caused by mutations in a the RPA1 gene.
Experience with techniques specifically relevant to hematopoietic stem cells and bone marrow failure disorders. Hands-on experience with gene editing. The role involves directly working on gene editing experiments Attention to detail and ability to carefully follow protocols. Gene editing work requires meticulous technique and record keeping.Create cell lines and inducible pluripotent stem cell lines with mutations of interest.Establish functional readouts .Interact and collaborate with multidisciplinary team to advance the program.
Proficiency with analysis programs like FlowJo, GraphPad Prism, etc. Useful for analyzing experimental results.Strong communication, collaboration and organizational skills. Important for working in a team environment.In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role.
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