Why Some People Have Never Gotten COVID

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5 reasons some people have never had COVID-19.

cannot be overstated. If a vaccinated person is exposed to the virus, they have a very good chance of avoiding contracting COVID altogether, Dr. Assoum explains.

to COVID variants like omicron or BA.2, for instance. Others may not pick up very mild or asymptomatic cases, or if there is a lower viral load in the body. That's why if you are symptomatic and received a negative result on a rapid at-home test, Dr. Assoum suggests getting a PCR test as well. If that's also negative, it's possible that your symptoms are due to a different infection, not COVID.

These five reasons can help explain why some people have never had a positive COVID-19 test. But is it possible for someone to be naturally resistant to the infection — to have some kind of innate immunity? Researchers have asked that very question, and are seeking to. By studying their protective genes, the scientists hope it can get them closer to developing virus-blocking drugs.

Having this kind of resistance is very rare; so much so, that it can be difficult to find people to study. And the scientists aren't sure what kind of resistance mechanisms they'll find. One idea is that"some people don't have a functioning ACE2 receptor, which SARS-CoV-2 uses to enter cells," an article in the

 

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