Why COVID-19 booster shots weren't tweaked to better match Delta variant

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More COVID-19 booster shots may be on the way — but when it’s your turn, you’ll get an extra dose of the original vaccine formulation, not one updated to better match the extra-contagious Delta variant.

Lab tests and real-world experience offer reassuring evidence that COVID-19 vaccines offer a high level of protection against the Delta variant.

Both companies first experimented with tweaked doses against the Beta variant that emerged in South Africa and has been the most vaccine-resistant to date. Lab tests showed the updated shots produced potent antibodies. But the Beta variant didn’t spread widely. The mRNA vaccines are considered the easiest kind to tweak, but some other vaccine makers also are exploring how to change their recipes if necessary.Moderna’s Dr. Jacqueline Miller told an FDA advisory panel last week the company is studying variant-specific boosters now to learn if they offer advantages, and to be ready if they’re needed.

 

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