What to know about antibody tests in a post-vaccine world

The CDC is warning against using commercial tests to determine immunity.

7/25/2021 12:01:00 PM

The CDC is warning against using commercial tests to determine immunity.

The CDC is warning against using commercial tests to determine immunity.

.But scientists are still searching for a so-called"correlate of protection" -- a marker in the blood that would reliably indicate protection. And they don't necessarily think it's antibodies. That means the presence of antibodies -- or even more specific antibody levels -- does not necessarily correlate with a person's level of protection.

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"The correlates of protection are not known, and so it is not known whether a positive antibody test after COVID-19 infection represents protection against any variant, including the delta variant," said Dr. Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center.

Tami Chappell/AFP via Getty Images, FILEA general view of the U.S. Centers for Disease Control and Prevention (CDC) headquarters in Atlanta, on April 24, 2020.The Food and Drug Administration strongly warns against antibody tests as a way to check for immunity among people who are fully vaccinated, writing in May that"currently authorized SARS-CoV-2 antibody tests should not be used to evaluate a person's level of immunity or protection from COVID-19 at any time, and especially after the person has received a COVID-19 vaccination." headtopics.com

Experts agreed that this warning might be confusing for some consumers. After all, antibody testing is routinely done to test for immunity against other viruses such as hepatitis B, measles, mumps, rubella and varicella.But COVID-19 is different, experts said.

"It is generally not recommended to use commercial antibody tests to monitor responses to vaccines, because the meaning of these assays has not been well defined in terms of whether they can predict vaccine protection or not," said Barouch.MORE: How 3 counties reached the highest COVID-19 vaccination rates in their states

We know the COVID-19 vaccines work not because of a blood test, but from large clinical trials that compared a group of unvaccinated people against a group of vaccinated people, finding that unvaccinated people were overwhelmingly more likely to become infected and fall seriously ill with COVID-19.

"What we generally think is that all of the vaccines get you to high-enough levels where even if they wane, you're still protected against hospitalization," Ellerin said."Because the vaccines have done such a great job, all of them, at preventing hospitalizations, we think, based on some of the modeling studies, that you only need 3% of your average neutralizing antibody response to keep you out of the hospital." headtopics.com

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Unfortunately, there is no commercially available antibody test that can tell us if we are truly immune to COVID-19 or how long any immunity gained through natural infection or vaccine-mediated will last.STOCK PHOTO/Getty ImagesA COVID antibody test in an undated stock photo.

According to the CDC and FDA, the only acceptable time to use an antibody test to check for immunity is if you have volunteered for a carefully monitored clinical study. Some people with immune compromised conditions -- like cancer or autoimmune diseases -- don't mount a good response to vaccines.

Read more: ABC News »

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Yup, only trust the government. 🙄 The only real immunity you will have if you get vaccinated. I stop reading anything that starts with 'the cdc...' This is how blacks are treated in Federal courts. I labeled my documents for Appellant court. District court has no jurisdiction but wants to influence an Appellate decision. District court says it will consider my motions anyway.

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CDC advisory committee voices support for immunocompromised people getting boostersCDC advisory committee voices support for immunocompromised people getting boosters. CDC advisory committee voices support for immunocompromised people getting boosters. Probably using dirty needles too 😳😩 CDC, 'BAĞIŞIKLIĞI BASKILANMIŞ KİŞİLER ' GÜÇLENDİRİCİ ALMALILAR DİYOR.! 2.DOZ AŞININ ÇÜRÜMÜŞ HİPOTEZLERİNE YENİ ARAYIŞTIR BU..! 3. DOZ AŞININDA ÇÖZÜM OLMADIĞINI WHO, CDC, FDA, EMA TÜM DÜNYA ANLAYACAKTIR. 3. DOZ DAHA ÇOK YAN ETKİLER YARATIR DEMEKTİR.! PROTEİN KAYNAKLI VİRÜS NEDİR.?

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